Has Keiko Ikeda found the core problem of AHC?

Dr. Keiko Ikeda Keiko Ikeda
Intl. Univ. Health and Welfare, Japan

Keiko´s lab has been working with knock-out mice (ATP1A3/ATP1A2) for 20 years.
They have found that not only is the Sodium/potassium pump not working properly but also the core transporters are not functioning properly.

Keiko Ikeda has completed MD, PhD from Lichi Medical University and worked as a postdoctoral fellow at Penn State University (USA) and at Genzentrum of Munchen University (Germany). Now she is a professor of Physiology in IUHW and is doing research in her laboratory.

A knockout mouse or knock-out mouse is a genetically modified mouse in which researchers have inactivated, or “knocked out”, an existing gene by replacing it or disrupting it with an artificial piece of DNA.